AN INTERACTION OF BENZENE METABOLITES REPRODUCES THE MYELOTOXICITY OBSERVED WITH BENZENE EXPOSURE

被引:208
作者
EASTMOND, DA [1 ]
SMITH, MT [1 ]
IRONS, RD [1 ]
机构
[1] CHEM IND INST TOXICOL,RES TRIANGLE PK,NC 27709
关键词
D O I
10.1016/0041-008X(87)90196-7
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:85 / 95
页数:11
相关论文
共 65 条
[1]   BENZENE-H-3 METABOLISM IN RABBIT BONE-MARROW [J].
ANDREWS, LS ;
SASAME, HA ;
GILLETTE, JR .
LIFE SCIENCES, 1979, 25 (07) :567-572
[2]   EFFECTS OF TOLUENE ON METABOLISM, DISPOSITION AND HEMATOPOIETIC TOXICITY OF [BENZENE-H-3 [J].
ANDREWS, LS ;
LEE, EW ;
WITMER, CM ;
KOCSIS, JJ ;
SNYDER, R .
BIOCHEMICAL PHARMACOLOGY, 1977, 26 (04) :293-300
[3]   DEVELOPMENT OF NEUTROPHILIC POLYMORPHONUCLEAR LEUKOCYTES IN HUMAN BONE MARROW - ORIGIN AND CONTENT OF AZUROPHIL AND SPECIFIC GRANULES [J].
BAINTON, DF ;
ULLYOT, JL ;
FARQUHAR, MG .
JOURNAL OF EXPERIMENTAL MEDICINE, 1971, 134 (04) :907-+
[4]  
BILLINGS RE, 1985, DRUG METAB DISPOS, V13, P287
[5]  
BRABEC MJ, 1981, PATTYS IND HYGIENE A, V2, P2629
[6]   ADRIAMYCIN - REVIEW [J].
CARTER, SK .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1975, 55 (06) :1265-1274
[7]  
CATHERS LE, 1986, TOXICOLOGIST, V6, P157
[8]   ROLE OF RADICAL CATIONS IN AROMATIC HYDROCARBON CARCINOGENESIS [J].
CAVALIERI, E ;
ROGAN, E .
ENVIRONMENTAL HEALTH PERSPECTIVES, 1985, 64 :69-84
[9]   OXIDATION OF PHENOL AND ITS REACTION-PRODUCT BY HORSERADISH-PEROXIDASE AND HYDROGEN-PEROXIDE [J].
DANNER, DJ ;
BRIGNAC, PJ ;
ARCENEAU.D ;
PATEL, V .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1973, 156 (02) :759-763
[10]  
EASTMOND DA, 1986, MOL PHARMACOL, V30, P674