CLEAVAGE BY BETA-GLUCURONIDASE OF WATER-SOLUBLE METABOLITES OF DIGITOXIN EXCRETED IN BILE OF CONTROL AND SPIRONOLACTONE-PRETREATED RATS

被引：24

作者：

CASTLE, MC ^{[1
]}

LAGE, GL ^{[1
]}

机构：

[1] UNIV KANSAS,SCH PHARM,DEPT PHARMACOL & TOXICOL,LAWRENCE,KS 66044

来源：

TOXICOLOGY AND APPLIED PHARMACOLOGY | 1974年 / 27卷 / 03期

关键词：

D O I：

10.1016/0041-008X(74)90043-X

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：641 / 647

页数：7

共 12 条

[1]

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[2]

CASTLE MC, 1973, RES COMMUN CHEM PATH, V5, P99

[3] EFFECT OF PRETREATMENT WITH SPIRONOLACTONE, PHENOBARBITAL OR BETA-DIETHYLAMINOETHYL DIPHENYLPROPYLACETATE (SKF 525-A) ON TRITIUM LEVELS IN BLOOD, HEART AND LIVER OF RATS AT VARIOUS TIMES AFTER ADMINISTRATION OF [H-3] DIGITOXIN [J].

CASTLE, MC ;

LAGE, GL .

BIOCHEMICAL PHARMACOLOGY, 1972, 21 (10) :1449-&

[4]

CASTLE MC, 1973, RES COMMUN CHEM PATH, V6, P601

[5]

CASTLE MC, 1973, ARCH INT PHARMACOD T, V203, P323

[6]

CASTLE MC, 1973, DRUG METAB DISPOS, V1, P590

[7]

KATZUNG BG, 1966, J PHARMACOL EXP THER, V154, P575

[8] EFFECT OF SPIRONOLACTON, ETACRYNIC ACID AND FUROSEMID ON MICROSOMAL ENZYMES OF RAT LIVER [J].

LEBER, HW ;

RAWER, P ;

SCHUTTERLE, G .

KLINISCHE WOCHENSCHRIFT, 1971, 49 (02) :116-+

[9]

OKITA GT, 1969, DIGITALIS

[10] DIGITOXIN POISONING - PREVENTION BY SPIRONOLACTONE [J].

SELYE, H ;

KRAJNY, M ;

SAVOIE, L .

SCIENCE, 1969, 164 (3881) :842-&

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