BACKBONE MODIFICATION OF CHIRASIL-VAL - EFFECT OF NONPOLAR SIDE-CHAINS ON ENANTIOMER SEPARATION IN GAS-CHROMATOGRAPHY

被引：10
作者：
KOPPENHOEFER, B
MUHLECK, U
LOHMILLER, K
机构：
[1] Institut für Organische Chemie der Universität, Tübingen, 72076
来源：
CHROMATOGRAPHIA | 1995年 / 40卷 / 11-12期
关键词：
GAS CHROMATOGRAPHY; ENANTIOMER SEPARATION; CHIRAL POLYSILOXANE; AMINO ACIDS; PHYSICOCHEMICAL PROPERTIES;
D O I：
10.1007/BF02315143
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The polysiloxane backbone of the gas chromatography phase Chirasil-Val has been modified by replacing one methyl group per dialkylsiloxy unit by pentyl and hexyl groups, respectively. The new phases offer the advantage of reduced polarities and softening points, while the separation factors (alpha) of enantiomeric pairs of N,O-trifluoroacetyl amino acid propyl esters show small but intriguing deviations from those determined on Chirasil-Val.
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收藏
页码：718 / 723
页数：6
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