Effects of pre-exposure vaccination and quarantine in the fight against ebola

Swift quarantine offers some hope in the fight against Ebola but its implementation faces some resistance in many settings. Hence, it is critical to explore whether introducing pre-exposure vaccination in an area where quarantine for the exposed and infected is already practiced would benefit the community with regard to controlling Ebola virus disease and vice versa. We present a mathematical model that explores the potential role of pre-exposure vaccination and quarantine in the fight against Ebola. Threshold parameter of the model is computed and rigorously analysed. Sensitivity analysis is carried out in an effort to understand the effects of constituent parameters on the threshold parameter. The results indicate that pre-exposure and quarantine are able to reduce the disease threshold parameter suggesting they offer hope of Ebola virus disease control.