DIASTEREOSELECTIVE OXIDATION OF SUBSTITUTED 1,2-DITHIOLAN-3-ONES

被引：11

作者：

GLASS, RS

LIU, YQ

机构：

[1] Department of Chemistry, The University of Arizona, Tucson

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 23期

关键词：

D O I：

10.1016/S0040-4039(00)76693-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Oxidation of 1,2-dithiolan-3-ones 1 with one equivalent of dimethyldioxirane in dichloromethane at -78 degrees C produces the corresponding 1,2-dithiolan-3-one 1-oxides 2 in high yield and with diastereoselectivities as high as 18:1. The major diastereomer formed is the trans isomer. An X-ray crystallographic structure study of the major diastereomer 2c obtained by oxidation of 1g is reported.

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页码：3887 / 3888

页数：2

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