Interaction of Glycyrrhizic Acid with the Products of Cholesterol Oxidation: a New View of the Problem of Atherosclerosis

被引:0
作者
Glushchenko, O. Yu. [1 ]
Polyakov, N. E. [1 ]
Leshina, T. V. [1 ]
机构
[1] Russian Acad Sci, Siberian Branch, Inst Chem Kinet & Combust, Ul Inst Skaya 3, Novosibirsk 630090, Russia
来源
CHEMISTRY FOR SUSTAINABLE DEVELOPMENT | 2011年 / 19卷 / 06期
关键词
cholesterol oxidation; ozone; glycyrrhizic acid; atherosclerosis; cholesterol complex;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The ability of glycyrrhizic acid to form complexes with the products of cholesterol oxidation was studied. The effect of complexing on the rate of cholesterol oxidation with ozone was studied. It was shown that the formation of complex with glycyrrhizic acid may become an efficient approach to govern the level of cholesterol inside and outside of cell membranes, and to extract the products of cholesterol oxidation.
引用
收藏
页码:605 / 609
页数:5
相关论文
共 13 条
  • [11] Tolstikov GA, 1997, BIOORG KHIM+, V23, P691
  • [12] Site-specific modification of Alzheimer's peptides by cholesterol oxidation products enhances aggregation energetics and neurotoxicity
    Usui, Kenji
    Hulleman, John D.
    Paulsson, Johan F.
    Siegel, Sarah J.
    Powers, Evan T.
    Kelly, Jeffery W.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (44) : 18563 - 18568
  • [13] Evidence for ozone formation in human atherosclerotic arteries
    Wentworth, P
    Nieva, J
    Takeuchi, C
    Galve, R
    Wentworth, AD
    Dilley, RB
    DeLaria, GA
    Saven, A
    Babior, BM
    Janda, KD
    Eschenmoser, A
    Lerner, RA
    [J]. SCIENCE, 2003, 302 (5647) : 1053 - 1056