Interaction of Glycyrrhizic Acid with the Products of Cholesterol Oxidation: a New View of the Problem of Atherosclerosis

被引：0
作者：
Glushchenko, O. Yu. [1 ]
Polyakov, N. E. [1 ]
Leshina, T. V. [1 ]
机构：
[1] Russian Acad Sci, Siberian Branch, Inst Chem Kinet & Combust, Ul Inst Skaya 3, Novosibirsk 630090, Russia
来源：
CHEMISTRY FOR SUSTAINABLE DEVELOPMENT | 2011年 / 19卷 / 06期
关键词：
cholesterol oxidation; ozone; glycyrrhizic acid; atherosclerosis; cholesterol complex;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The ability of glycyrrhizic acid to form complexes with the products of cholesterol oxidation was studied. The effect of complexing on the rate of cholesterol oxidation with ozone was studied. It was shown that the formation of complex with glycyrrhizic acid may become an efficient approach to govern the level of cholesterol inside and outside of cell membranes, and to extract the products of cholesterol oxidation.
引用
收藏
页码：605 / 609
页数：5
相关论文
共 13 条
  • [1] Solubilization of cholesterol in aqueous solution by two β-cyclodextrin dimers and a negatively charged β-cyclodextrin derivative
    Alvarez Alcalde, Mercedes
    Antelo, Alvaro
    Jover, Aida
    Meijide, Francisco
    Vazquez Tato, Jose
    [J]. JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, 2009, 63 (3-4) : 309 - 317
  • [2] Antiviral effects of Glycyrrhiza species
    Fiore, Cristina
    Eisenhut, Michael
    Krausse, Rea
    Ragazzi, Eugenio
    Pellati, Donatella
    Armanini, Decio
    Bielenberg, Jens
    [J]. PHYTOTHERAPY RESEARCH, 2008, 22 (02) : 141 - 148
  • [3] Licorice extract and its major polyphenol glabridin protect low-density lipoprotein against lipid peroxidation: In vitro and ex vivo studies in humans and in atherosclerotic apolipoprotein E-deficient mice
    Fuhrman, B
    Buch, S
    Vaya, J
    Belinky, PA
    Coleman, R
    Hayek, T
    Aviram, M
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 1997, 66 (02) : 267 - 275
  • [4] CELLULAR CHOLESTEROL EFFLUX MEDIATED BY CYCLODEXTRINS
    KILSDONK, EPC
    YANCEY, PG
    STOUDT, GW
    BANGERTER, FW
    JOHNSON, WJ
    PHILLIPS, MC
    ROTHBLAT, GH
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (29) : 17250 - 17256
  • [5] Oxidized products of cholesterol: dietary and metabolic origin, and proatherosclerotic effects (review)
    Leonarduzzi, G
    Sottero, B
    Poli, G
    [J]. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2002, 13 (12) : 700 - 710
  • [6] Effects of trace components of dietary fat on cholesterol metabolism: Phytosterols, oxysterols, and squalene
    Ostlund, RE
    Racette, SB
    Stenson, WF
    [J]. NUTRITION REVIEWS, 2002, 60 (11) : 349 - 359
  • [7] Antioxidant and redox properties of supramolecular complexes of carotenoids with β-glycyrrhizic acid
    Polyakov, N. E.
    Leshina, T. V.
    Salakhutdinov, N. F.
    Konovalova, T. A.
    Kispert, L. D.
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 2006, 40 (10) : 1804 - 1809
  • [8] Poole C.P., 1971, RELAXATION MAGNETIC, P392
  • [9] Formation of biologically active oxysterols during ozonolysis of cholesterol present in lung surfactant
    Pulfer, MK
    Murphy, RC
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (25) : 26331 - 26338
  • [10] Ozonation of cholesterol in the presence of ethanol: Identification of a cytotoxic ethoxyhydroperoxide molecule
    Tagiri-Endo, M
    Nakagawa, K
    Sugawara, T
    Ono, K
    Miyazawa, T
    [J]. LIPIDS, 2004, 39 (03) : 259 - 264
12