RATE OF SISTER CHROMATID EXCHANGE IN NORMAL HUMAN-BONE MARROW-CELLS

被引：17

作者：

BECHER, R

SCHMIDT, CG

THEIS, G

HOSSFELD, DK

机构：

[1] Westdeutsches Tumorzentrum, Innere Universitätsklinik und Poliklinik (Tumorforschung), Essen 1, D-4300

来源：

HUMAN GENETICS | 1979年 / 50卷 / 02期

关键词：

D O I：

10.1007/BF00390243

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Sister chromatid exchange (SCE) was studied in bone marrow cells of six healthy individuals. Compared with peripheral blood lymphocytes, a remarkably low and constant rate of SCEs was observed, ranging from 3.64 to 4.65 per metaphase. The lower incidence of SCE can be related only partly to the higher contraction of bone marrow cells and the shorter exposure time to BUdR. Rather, a cell-specific phenomenon is suggested. © 1979 Springer-Verlag.

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页码：213 / 216

页数：4

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