HISTOLOGICAL EXAMINATION OF SURFACE REPAIR TISSUE AFTER SUCCESSFUL OSTEOTOMY FOR OSTEOARTHRITIS OF THE HIP-JOINT

被引：11

作者：

ITOMAN, M

YAMAMOTO, M

YONEMOTO, K

SEKIGUCHI, M

KAI, H

机构：

[1] Department of Orthopaedic Surgery, Kitasato University School of Medicine, Kanagawa, 228, Kitasato 1-15-1, Sagamihara

来源：

INTERNATIONAL ORTHOPAEDICS | 1992年 / 16卷 / 02期

关键词：

D O I：

10.1007/BF00180199

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

In this study biopsy specimens of the surface repair tissue from the weightbearing area of the hip joint were collected from 15 patients who had undergone successful valgus osteotomy, and these were examined histologically. In 6 of the 15 patients the specimens stained strongly with safranin-O in all three layers of the matrix. However, the repair tissue from another 6 patients showed strong staining only in the intermediate and deep layers, while that from 2 patients stained only in the deep layer. Specimens from 5 patients were stained for S-100 protein and positive cells were detected in all cases, demonstrating that the cells in the repair tissue were chondrocytes. However, there was no tide mark in the repair tissue and the arrangement of the cells differed from that in normal cartilage. Discontinuity of the subchondral bone was also noted. These findings make it likely that the repair tissue was of bone marrow origin.

引用

页码：118 / 121

页数：4

共 15 条

[1]

Campbell C.J., The healing of cartilage defects, Clin Orthop, 64, pp. 45-63, (1969)

[2]

Depalma A.F., McKeever C.D., Subin S.K., Process of repair of articular cartilage demonstrated by histology and autoradiography with tritiated thymidine, Clin Orthop, 48, pp. 229-242, (1966)

[3]

Frost G.E., Cartilage healing and regeneration, J South African Veter Assoc, 50, pp. 181-187, (1979)

[4]

Itoman M., Morita M., Yamamoto M., Sasamoto N., Biomechanical significance of valgus-extension osteotomy (Bombelli) for advanced coxarthrosis, The hip, pp. 53-58, (1984)

[5]

Itoman M., Valgus-flexion osteotomy for severely advanced osteoarthritis of the hip joint in middle-aged patients, J Inter Coll Surg Thailand, 30, pp. 21-23, (1988)

[6]

Itoman M., Yonemoto K., Sekiguchi M., Yamamoto M., Valgus-flexion osteotomy in middle-aged patients with advanced osteoarthritis of the hip: a clinical and radiological evaluation, J Jpn Orthop Assoc, 66, pp. 195-204, (1992)

[7]

Maistrelli G.L., Gerundini M., Fusco U., Bombelli R., Bombelli A.A., Valgus-extension osteotomy for osteoarthritis of the hip, J Bone Joint Surg, 72, pp. 653-657, (1990)

[8]

Mankin J.H.J., Boyle C.J., The acute effects of lacerative injury on DNA and protein synthesis in articular cartlage, Cartilage degeneration and repair, pp. 185-199, (1967)

[9]

Mankin H.J., Dorfman H., Lipiello L., Zarins A., Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips: II. Correlation of morphology with biochemical and metabolic data, J Bone Joint Surg, 53, pp. 523-537, (1971)

[10]

Mankin H.J., The reaction of articular cartilage to injury and osteoarthritis, New England J Med, 291, pp. 1285-1292, (1974)

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