REFRACTORINESS OF ERYTHROCYTES INFECTED WITH PLASMODIUM-FALCIPARUM GAMETOCYTES TO LYSIS BY SORBITOL

被引：25
|
作者：
SAUL, A
GRAVES, P
EDSER, L
机构：
[1] Queensland Institute of Medical Research, Brisbane, QLD 4006, Bramston Terrace, Herston
来源：
INTERNATIONAL JOURNAL FOR PARASITOLOGY | 1990年 / 20卷 / 08期
基金：
英国医学研究理事会;
关键词：
PLASMODIUM-FALCIPARUM; GAMETOCYTES; SCHIZONTS; SORBITOL LYSIS; SYNCHRONIZATION;
D O I：
10.1016/0020-7519(90)90056-S
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Unlike erythrocytes infected with mature asexual parasites of Plasmodium falciparum, those infected with gametocytes are not lysed by 5% sorbitol solutions. This observation was used to devise a method for producing synchronized cultures of gametocytes, free of asexual stage parasites. The refractoriness to sorbitol suggests that the major anion transport pathway, which appears in the membrane of erythrocytes infected with asexual stage parasites, is not present in cells infected with gametocytes.
引用
收藏
页码：1095 / 1097
页数：3
相关论文
共 50 条
  • [41] Downstream effects of haemoglobinase inhibition in Plasmodium falciparum-infected erythrocytes
    Naughton, Julie A.
    Nasizadeh, Sima
    Bell, Angus
    MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2010, 173 (02) : 81 - 87
  • [42] Cryo scanning electron microscopy of Plasmodium falciparum-infected erythrocytes
    Hempel, Casper
    APMIS, 2017, 125 (07) : 650 - 654
  • [43] OPTIMIZATION AND INHIBITION OF THE ADHERENT ABILITY OF PLASMODIUM-FALCIPARUM-INFECTED ERYTHROCYTES
    SMITH, H
    CRANDALL, I
    PRUDHOMME, J
    SHERMAN, IW
    MEMORIAS DO INSTITUTO OSWALDO CRUZ, 1992, 87 : 303 - 312
  • [44] The role of aminopeptidases in haemoglobin degradation in Plasmodium falciparum-infected erythrocytes
    Gavigan, CS
    Dalton, JP
    Bell, A
    MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2001, 117 (01) : 37 - 48
  • [45] Plasmodium falciparum selectively degrades α-spectrin of infected erythrocytes after invasion
    Zheng, Kexin
    Li, Qilong
    Jiang, Ning
    Zhang, Yanxin
    Zheng, Yuxin
    Zhang, Yiwei
    Feng, Ying
    Chen, Ran
    Sang, Xiaoyu
    Chen, Qijun
    MBIO, 2024, 15 (04):
  • [46] Plasmodium falciparum:: The importance of IgM in the resetting of parasite-infected erythrocytes
    Clough, B
    Atilola, FA
    Black, J
    Pasvol, G
    EXPERIMENTAL PARASITOLOGY, 1998, 89 (01) : 129 - 132
  • [47] A PLASMODIUM-FALCIPARUM GENE CODING FOR A 15-KILODALTON ANTIGEN EXPRESSED IN ASEXUAL STAGE PARASITES, GAMETOCYTES AND GAMETES
    LANGSLEY, G
    KASLOW, DC
    BARBOT, P
    BLISNICK, T
    PONNUDURAI, T
    BARALE, JC
    BRAUNBRETON, C
    MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1992, 55 (1-2) : 221 - 224
  • [48] Plasmodium falciparum phosphoenolpyruvate carboxykinase is developmentally regulated in gametocytes
    Hayward, RE
    MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2000, 107 (02) : 227 - 240
  • [49] Stevor transcripts from Plasmodium falciparum gametocytes encode truncated polypeptides
    Sutherland, CJ
    MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2001, 113 (02) : 331 - 335
  • [50] Antibody responses to surface antigens of Plasmodium falciparum gametocyte-infected erythrocytes and their relation to gametocytaemia
    Dinko, B.
    King, E.
    Targett, G. A. T.
    Sutherland, C. J.
    PARASITE IMMUNOLOGY, 2016, 38 (06) : 352 - 364
12345