MONOCLONAL-ANTIBODY DIFFERENTIATES CHICKEN A-SYSTEM ALLOANTIGENS

被引：4
|
作者：
FULTON, JE
BRILES, RW
LAMONT, SJ
机构：
[1] IOWA STATE UNIV SCI & TECHNOL,DEPT ANIM SCI,AMES,IA 50011
[2] IOWA STATE UNIV SCI & TECHNOL,IMMUNOBIOL PROGRAM,AMES,IA 50011
[3] NO ILLINOIS UNIV,DEPT BIOL SCI,DE KALB,IL 60115
来源：
ANIMAL GENETICS | 1990年 / 21卷 / 01期
关键词：
blood group A; chicken; erythrocyte antigen; monoclonal antibody;
D O I：
10.1111/j.1365-2052.1990.tb03205.x
中图分类号：
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号：
0905 ;
摘要：
Summary A monoclonal antibody (ISU‐cA) was produced that recognized certain alloantigens of the chicken A blood group locus. Antigens produced by alleles A3, A4 and A8 were positive, and those produced by A2 and A5 were negative, by haemagglutination. The specificity of ISU‐cA for chicken A blood group antigens was demonstrated by serologic analyses, genetic crosses and competitive inhibition of binding by anti‐A alloantisera. To our knowledge, this is the first reported monoclonal antibody against a chicken blood group alloantigen system other than the B complex. 1990 International Society for Animal Genetics
引用
收藏
页码：39 / 45
页数：7
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