NOVEL GERM-CELL TUMOR-CELL LINE ESTABLISHED FROM A TESTICULAR FEMINIZATION SYNDROME

被引：0

作者：

IMAMURA, K ^{[1
]}

KIYOZUKA, Y ^{[1
]}

NISHIMURA, H ^{[1
]}

YAKUSHIJI, M ^{[1
]}

机构：

[1] KURUME UNIV,SCH MED,DEPT PATHOL 2,KURUME,FUKUOKA 830,JAPAN

来源：

ONCOLOGY REPORTS | 1995年 / 2卷 / 01期

关键词：

GERM CELL TUMOR CELL LINE; TESTICULAR FEMINIZATION SYNDROME;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We analyzed a novel cell line established from a testicular feminization syndrome. The original tumor was an endodermal sinus tumor with seminoma. The doubling time, the saturation density and the mitotic index were 36.1 hours, 3.65x10(4) cells/cm2 and 4.3%, respectively. The mode number of chromosomes was 102. Results of the MTT assay showed that the cell line had an IC50/PPC of less than 0.1 for methotrexate and actinomycin D. The effects of methotrexate were schedule dependent; the effects of actinomycin D were both schedule and dose dependent.

引用

页码：17 / 25

页数：9

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