EFFECTS OF NIZATIDINE ON GASTRIC-ACID AND BICARBONATE SECRETION

被引:0
|
作者
VIANELLO, F [1 ]
LAINO, G [1 ]
DALSANTO, P [1 ]
DELBIANCO, T [1 ]
GERMANA, B [1 ]
FARINATI, F [1 ]
MARTIN, A [1 ]
BATTAGLIA, G [1 ]
PLEBANI, M [1 ]
DIMARIO, F [1 ]
机构
[1] UNIV PADUA,INST GEN MED,DIV GASTROENTEROL,I-35100 PADUA,ITALY
关键词
D O I
10.1016/S0011-393X(05)80786-6
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The effects of nizatidine on human gastric parietal secretion (volume and acid output) and nonparietal secretion (volume and bicarbonate concentration and secretion) were evaluated in 18 patients with duodenal ulcer. Nizatidine reduced the volume of pentagastrin-stimulated gastric secretion and gastric acid secretion. Nizatidine also decreased the volume of nonparietal secretion and bicarbonate secretion, although bicarbonate concentration remained unchanged.
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页码:277 / 284
页数:8
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