A DIECKMANN/RING EXPANSION APPROACH TO TETRAHYDROPYRIDO[1,2-A]INDOLES AND TETRAHYDROAZEPINO[1,2-A]INDOLES

被引：29

作者：

BIT, RA ^{[1
]}

DAVIS, PD ^{[1
]}

HILL, CH ^{[1
]}

KEECH, E ^{[1
]}

VESEY, DR ^{[1
]}

机构：

[1] ROCHE PROD LTD,POB 8,WELWYN GARDEN CIT AL7 3AY,HERTS,ENGLAND

来源：

TETRAHEDRON | 1991年 / 47卷 / 26期

关键词：

D O I：

10.1016/S0040-4020(01)86471-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general Dieckmann/ring expansion approach to fused [1,2-a]indole systems is reported. This approach has allowed the synthesis of a large variety of substituted systems required for the preparation of a series of potent and selective inhibitors of Protein Kinase C.

引用

页码：4645 / 4664

页数：20

共 22 条

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