LIPASE-MEDIATED DIASTEREOSELECTIVE HYDROLYSIS OF STEROIDAL 3-(O-CARBOXYMETHYL) OXIME METHYL-ESTERS

被引：12

作者：

ADAMCZYK, M

CHEN, YY

FISHPAUGH, JR

GEBLER, JC

机构：

[1] Divisional Chemistry D-9NM, Abbott Diagnostics Division, Abbott Laboratories, Abbott Park

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 07期

关键词：

D O I：

10.1016/S0957-4166(00)80344-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A series of geometric isomeric mixtures of steroidal 3-(O-carboxymethyl) oxime methyl esters 1-4 were hydrolyzed with high diastereoselectivity for the anti isomer with crude lipase from Candida cylindracea.

引用

页码：1467 / 1468

页数：2

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