Cellular aging and senescence

被引：54
|
作者：
McCormick, Anna [1 ]
Campisi, Judith [2 ]
机构：
[1] NIA, Biol Aging Program, Bethesda, MD 20892 USA
[2] Univ Calif Berkeley, Lawrence Berkeley Natl Lab, Div Cell & Mol Biol, Berkeley, CA 94720 USA
来源：
CURRENT OPINION IN CELL BIOLOGY | 1991年 / 3卷 / 02期
关键词：
D O I：
10.1016/0955-0674(91)90144-N
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Differentiated eukaryotic cells have only a finite capacity for cell division. This limitation is thought to be a cellular manifestation of organismal aging, and a restraint to tumor progression. The molecular basis for cellular senescence is not known, but a molecular framework for understanding this phenomenon has recently been established.
引用
收藏
页码：230 / 234
页数：5
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