PRODUCTION OF ANTIBODIES TO CATECHOL-O-METHYLTTANSFERASE (EC 2.1.1.6) OF RAT LIVER

被引：17
作者：
ASSICOT, M
BOHUON, C
机构：
[1] Laboratoire de Biologie Clinique et Expérimentale, Institut Gustave Roussy
来源：
BIOCHEMICAL PHARMACOLOGY | 1969年 / 18卷 / 08期
关键词：
D O I：
10.1016/0006-2952(69)90284-6
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
A potent and specific antibody to the catechol-O-methyltransferase (EC 2.1.1.6) has been produced in rabbits by injecting the purified enzyme from rat liver. This antibody inhibited the catechol-O-methyltransferase from various organs of the rat and from liver of some mammalian species. The specificity of the antibody was demonstrated by the lack of inhibition of several other O-ethylating enzymes. The usefulness of this antibody for pharmacological research is emphasized. © 1969.
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页码：1893 / &
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