MOLECULAR CHARACTERIZATION OF FRPB, THE 70-KILODALTON IRON-REGULATED OUTER-MEMBRANE PROTEIN OF NEISSERIA-MENINGITIDIS

被引：44
作者：
PETTERSSON, A
MAAS, A
VANWASSENAAR, D
VANDERLEY, P
TOMMASSEN, J
机构：
[1] UNIV UTRECHT,INST BIOMEMBRANES,3584 CH UTRECHT,NETHERLANDS
[2] UNILEVER RES LABS,3133 AT VLAARDINGEN,NETHERLANDS
[3] NATL INST PUBL HLTH & ENVIRONM PROTECT,3720 BA BILTHOVEN,NETHERLANDS
来源：
INFECTION AND IMMUNITY | 1995年 / 63卷 / 10期
关键词：
D O I：
10.1128/IAI.63.10.4181-4184.1995
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The structural gene encoding the 70-kDa outer membrane protein FrpB of Neisseria meningitidis was cloned and sequenced. A mutant lacking FrpB was constructed. No difference in iron utilization between the mutant and the parental strain was observed. A minor effect of the mutation on serum resistance was observed. A topology model for FrpB in the outer membrane is proposed.
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页码：4181 / 4184
页数：4
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