24-HOUR INTRAGASTRIC PH MEASUREMENT IN THE ASSESSMENT OF DUODENOGASTRIC REFLUX

被引:11
作者
BROWN, TH [1 ]
HOLBROOK, I [1 ]
KING, RFG [1 ]
IBRAHIM, K [1 ]
机构
[1] HOPE HOSP,DEPT BIOCHEM,SALFORD M6 8HD,LANCS,ENGLAND
关键词
D O I
10.1007/BF02067015
中图分类号
R61 [外科手术学];
学科分类号
摘要
In this study we compared the results of measurement of duodenogastric reflux using 24-hour intragastric pH monitoring and nasogastric aspiration with analysis of bile acid and alpha amylase concentrations. Eight patients were studied at least 5 months after biliary and/or gastric surgery. The correlation coefficient of pH and bile acid concentration was 0.36 (p < 0.001) and of pH and amylase concentration was 0.48 (p < 0.001). If a pH > 4.0 was taken to indicate duodenogastric reflux this had a sensitivity of 84% compared with either high bile acid or amylase concentration. Bile acid concentration has been the "standard" method of measuring duodenogastric reflux. pH monitoring is relatively simple to perform, causes little patient distress, and can measure episodes of duodenogastric reflux over a continuous 24-hour period.
引用
收藏
页码:995 / 1000
页数:6
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