RING TRANSFORMATIONS OF HETEROCYCLES .1. TRANSFORMATION OF 4-AMINO-DELTA-2-1,2,4-OXADIAZOLINES INTO 1,3,4-OXADIAZOLES

被引：9

作者：

ELABADELAH, MM ^{[1
]}

NAZER, MZ ^{[1
]}

HUSSEIN, AQ ^{[1
]}

AWADALLAH, AM ^{[1
]}

RADEMACHER, P ^{[1
]}

WOYDT, M ^{[1
]}

机构：

[1] UNIV ESSEN GESAMTHSCH,INST ORGAN CHEM,W-4300 ESSEN 1,GERMANY

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1991年 / 28卷 / 05期

关键词：

D O I：

10.1002/jhet.5570280513

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-Aryl-4-amino-DELTA-2-1,2,4-oxadiazolines 3 and their N-chloroacetyl derivatives 4, upon treatment with chloroacetic anhydride in refluxing toluene, afford 2-chloromethyl-5-aryl-1,3,4-oxadiazoles 5, suggesting the conversion sequence 3 --> 4 --> 5. The generality of the new ring transformation 4 --> 5 is supported similar conversion of other 4-(acylamino)-1,2,4-oxadiazolines 8 to 1,3,4-oxadiazoles 9.

引用

页码：1229 / 1234

页数：6

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