A SIMPLE STEREOSELECTIVE SYNTHESIS OF A TETRACYCLIC C-14 GINKGOLIDE

被引:24
作者
COREY, EJ
KAMIYAMA, K
机构
[1] Department of Chemistry, Harvard University, Cambridge
关键词
D O I
10.1016/S0040-4039(00)94481-2
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A short and efficient total synthesis of the structurally interesting tetracyclic ginkgolide derivative (±)-2 is described. © 1990.
引用
收藏
页码:3995 / 3998
页数:4
相关论文
共 9 条
[1]  
BRAQUET P, 1987, Drugs of the Future, V12, P643
[2]  
BRAQUET P, 1988, GINKGOLIDES CHEM PHA, V1
[3]  
COOPER K, 1989, ANNU REP MED CHEM, V24, P81
[4]   ENANTIOSELECTIVE ROUTE TO A KEY INTERMEDIATE IN THE TOTAL SYNTHESIS OF GINKGOLIDE-B [J].
COREY, EJ ;
GAVAI, AV .
TETRAHEDRON LETTERS, 1988, 29 (26) :3201-3204
[5]   TOTAL SYNTHESIS OF (+/-)-GINKGOLIDE-B [J].
COREY, EJ ;
KANG, M ;
DESAI, MC ;
GHOSH, AK ;
HOUPIS, JN .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (02) :649-651
[6]   SIMPLE ANALOGS OF GINKGOLIDE-B WHICH ARE HIGHLY-ACTIVE ANTAGONISTS OF PLATELET ACTIVATING FACTOR [J].
COREY, EJ ;
GAVAI, AV .
TETRAHEDRON LETTERS, 1989, 30 (50) :6959-6962
[7]   PLATELET-ACTIVATING-FACTOR - A BIOLOGICALLY-ACTIVE PHOSPHOGLYCERIDE [J].
HANAHAN, DJ .
ANNUAL REVIEW OF BIOCHEMISTRY, 1986, 55 :483-509
[8]   ANIONIC ACTIVATION OF STABILIZED YLIDES - A HIGHLY Z-STEREOSELECTIVE WITTIG REACTION OF (3-ETHOXYCARBONYL-2-OXOPROPYLIDENE)TRIPHENYL-PHOSPHORANE WITH ALIPHATIC-ALDEHYDES [J].
PIETRUSIEWICZ, KM ;
MONKIEWICZ, J .
TETRAHEDRON LETTERS, 1986, 27 (06) :739-742
[9]   INTRAMOLECULAR C-H INSERTION - SYNTHESIS OF (+/-)-PENTALENOLACTONE-E METHYL-ESTER [J].
TABER, DF ;
SCHUCHARDT, JL .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (18) :5289-5290