Gastric neuroendocrine carcinoma with positive staining for prostate cancer markers including prostate-specific antigen and alpha-methylacyl-CoA racemase

被引：0

作者：

Hakozaki, Yuji ^{[1
]}

Murata, Taro ^{[1
]}

Yokoyama, Munehiro ^{[2
]}

Matsushima, Hisashi ^{[1
]}

Ogawa, Maki ^{[2
]}

Masuda, Tomoko ^{[1
]}

Hirai, Yoko ^{[1
]}

Kume, Haruki ^{[3
]}

机构：

[1] Tokyo Metropolitan Police Hosp, Dept Urol, Tokyo, Japan

[2] Tokyo Metropolitan Police Hosp, Dept Pathol, Tokyo, Japan

[3] Univ Tokyo, Grad Sch Med, Dept Urol, Tokyo, Japan

来源：

UROLOGY CASE REPORTS | 2018年 / 20卷

关键词：

Gastric neuroendocrine carcinoma; Immunohistochemistry; Prostate cancer;

D O I：

10.1016/j.eucr.2018.07.008

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case with prostate cancer and gastric neuroendocrine carcinoma. A 72-year old male presented with a gastric lesion 5 months after radical prostatectomy. The lesion was immunohistochemically positive for PSA, alpha-methylacyl-CoA racemase, synaptophysin, and chromogranin A, but negative for androgen receptor (AR). Differentiating gastric neuroendocrine carcinoma from gastric metastasis of prostate cancer is difficult, as both lesions exhibit similar acinar cell proliferation with prominent nucleoli.(1) We discuss the diagnostic process of this case and how AR was a useful specific marker for diagnosing primary gastric neuroendocrine carcinoma.

引用

页码：67 / 69

页数：3

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