EFFECT OF LESIONS IN SEPTAL AREA AND OLFACTORY BULBS ON SODIUM CHLORIDE INTAKE

被引：39

作者：

CHIARAVIGLIO, E

机构：

[1] Instituto de Investigación Médica, Mercedes y Martín Ferreyra, Córdoba, Argentina2 2 The author wishes to thank Dr. Samuel Taleisnik, Director of the Instituto de Investigación Médica Mercedes y Martin Ferreyra for his valuable help.

来源：

PHYSIOLOGY & BEHAVIOR | 1969年 / 4卷 / 05期

关键词：

Drinking behavior; Limbic system; Saline preference; Sodium deprivation; Sodium excretion; Sodium overload;

D O I：

10.1016/0031-9384(69)90102-4

中图分类号：

B84 [心理学];

学科分类号：

04 ; 0402 ;

摘要：

Spontaneous sodium chloride intake in rats with lesions in the septal area or olfactory bulbs and normal rats were studied. Normal rats prefer 1% NaCl solutions when allowed to choose concentrations from 0.5%-3% NaCl and tap water. Animals with septal area or olfactory bulb lesions increase the 1% NaCl intake as compared with prelesion values. This effect was still evident 4 months later. The high NaCl intake is not related to an altered renal sodium excretion. The sodium depletion leads to a significant increase of Na intake in all animals, but the highest values are observed in lesioned animals. In Na-depleted rats, sodium overload reduced the sodium ingestion to normal values. It is postulated that, in the regulation of Na intake, a dual mechanism exists, inhibitory and stimulatory, and that the limbic system may be related to the inhibitory influences. © 1969.

引用

页码：693 / +

页数：1

共 16 条

[1]

ANDERSSON B, 1962, 22 P INT C PHYS SCI, V1, P661

[2] COMMONALITY AND SPECIFICITY OF BEHAVIORAL DYSFUNCTIONS FOLLOWING SEPTAL AND HIPPOCAMPAL LESIONS IN RATS [J].