SYNTHESIS AND CHARACTERIZATION OF LITHIUM AMINOBOROHYDRIDES - A NEW CLASS OF POWERFUL REDUCING AGENTS

被引：50

作者：

FISHER, GB ^{[1
]}

HARRISON, J ^{[1
]}

FULLER, JC ^{[1
]}

GORALSKI, CT ^{[1
]}

SINGARAM, B ^{[1
]}

机构：

[1] UNIV CALIF SANTA CRUZ,DEPT CHEM & BIOCHEM,SANTA CRUZ,CA 95064

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 32期

关键词：

D O I：

10.1016/S0040-4039(00)61305-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Lithium aminoborohydrides (LiABH3), obtained by the reaction of n-BuLi with amine-boranes, are powerful reducing agents, comparable to lithium aluminum hydride, yet selective in their reducing properties. LiABH3's reduce esters, lactones, and anhydrides to the corresponding alcohols, while carboxylic acids are not reduced. Test reductions show that LiABH3's also reduce a wide range of functional groups, including amides, epoxides, oximes, nitriles, and halides.

引用

页码：4533 / 4536

页数：4

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