Viscoelastic modulus of agarose gels by magnetic resonance elastography using Micro-MRI

被引：5

作者：

Suzuki, Hayato ^{[1
]}

Tadano, Shigeru ^{[2
]}

Goto, Mototeru ^{[1
]}

Yamada, Satoshi ^{[2
]}

Fujisaki, Kazuhiro ^{[3
]}

Kajiwara, Itsuro ^{[2
]}

Suga, Mikio ^{[4
]}

Nakamura, Gen ^{[5
]}

机构：

[1] Hokkaido Univ, Grad Sch Engn, Div Human Mech Syst & Design, Kita Ku, Kita 13,Nishi 8, Sapporo, Hokkaido 0608628, Japan

[2] Hokkaido Univ, Fac Engn, Div Human Mech Syst & Design, Kita Ku, Sapporo, Hokkaido 0608628, Japan

[3] Fac Sci & Technol, Dept Intelligent Machines & Syst Engn, Hirosaki, Aomori 0368560, Japan

[4] Chiba Univ, Grad Sch Engn, Div Artificial Syst Sci, Dept Med Syst Engn,Inage Ku, Chiba, Chiba 2638522, Japan

[5] Hokkaido Univ, Fac Sci, Dept Math, Kita Ku, Sapporo, Hokkaido 0600810, Japan

来源：

MECHANICAL ENGINEERING JOURNAL | 2015年 / 2卷 / 03期

基金：

日本科学技术振兴机构; 日本学术振兴会;

关键词：

Magnetic resonance elastography; Magnetic resonance imaging; Viscoelasticity; Soft matter stiffness; Elastic modulus;

D O I：

10.1299/mej.14-00417

中图分类号：

TH [机械、仪表工业];

学科分类号：

0802 ;

摘要：

This study aimed to apply magnetic resonance elastography (MRE) using micro-magnetic resonance imaging (micro-MRI) system for the measurements of viscoelastic modulus in soft matters. The rectangular specimens of 90 x 70 x 50 mm were made of agarose gel with five kinds of stiffness by changing concentrations. The specimens were oscillated with longitudinal waves transmitted by an elastic-bar from a vibration generator in a micro-MRI system. Since the viscoelastic properties depend on the excitation frequency and amplitude, the experimental conditions were selected in the range of 50-250 Hz and 0.1-0.5 mm. The viscoelastic modulus was expressed as storage shear modulus G' and loss shear modulus G". As a result, G' increased with the frequency and amplitude, and the difference of G' between hard and soft gels was obtained. The viscoelastic modulus of agarose gels was measured using the MRE system under the excitation conditions. Furthermore, double-layer specimens composed of 0.6 and 2.0 wt% gels were examined as an application of the MRE system. The difference of wave pattern between the hard and soft parts was observed. The values of G' in the soft parts of the double-layer specimens corresponded to the value of the single-layer specimen, but the values of G' in the hard parts were varied.

引用

页数：9

共 26 条

[1] Assessment of liver viscoelasticity using multifrequency MR elastography [J].