PRIMARY CENTRAL WHITE-MATTER DEGENERATION IN OLD DOGS

被引：24
作者：
FERRER, I
PUMAROLA, M
RIVERA, R
ZUJAR, MJ
CRUZSANCHEZ, F
VIDAL, A
机构：
[1] UNIV AUTONOMA BARCELONA, FAC MED, NEUROL TISSUE BANK, BARCELONA, SPAIN
[2] UNIV AUTONOMA BARCELONA, SCH VET, DEPT PATHOL, BARCELONA, SPAIN
来源：
ACTA NEUROPATHOLOGICA | 1993年 / 86卷 / 02期
关键词：
AGING; WHITE MATTER; UBIQUITIN; GALACTOCEREBROSIDE;
D O I：
10.1007/BF00334884
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Degeneration of the central white matter is described in old dogs. The presence of ubiquitin-immunoreactive free granules and intracytoplasmic globules in glial cells and macrophages, together with galactocerebroside-immunoreactive precipitates and lipofuscin storage, point to the likelihood of a primary myelin degeneration with deposits of non-degraded ubiquitin-protein conjugates and complex galactolipids.
引用
收藏
页码：172 / 175
页数：4
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