STRYCHNINE INTOXICATION

被引：13

作者：

GORDON, AM

RICHARDS, DW

机构：

[1] Division of General Medicine, Department of Medicine, University of Miami-Jackson Memorial Medical Center, Miami, FL

来源：

JACEP-JOURNAL OF THE AMERICAN COLLEGE OF EMERGENCY PHYSICIANS | 1979年 / 8卷 / 12期

关键词：

poisoning; strychnine; intoxication;

D O I：

10.1016/S0361-1124(79)80299-3

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Strychnine intoxication is manifested by agitation, muscle spasms, and convulsions. We report a case in which intractable convulsions led to severe lactic acidosis which secondarily resulted in visceral (lung, heart, kidney, liver, and brain) collapse and death. Aggressive therapy instituted in the emergency department and aimed at control of seizure activity and lactic acidosis may be lifesaving. © 1979 American College of Emergency Physicians.

引用

页码：520 / 522

页数：3

共 8 条

[1] Gosselin, Hodge, Smith, Et al., Clinical Toxiciology of Commercial Products, pp. 303-307, (1976)
[2] Teitelbaum, Ott, Acute strychnine intoxication, Clin Toxicol, 3, pp. 267-273, (1970)
[3] Goodman, Gilman, The Pharmacological Basis of Therapeutics, (1975)
[4] Sparagli, Mannaioni, Pharmacokinetic Observations on a Case of Massive Strychnine Poisoning, Clinical Toxicology, 6, pp. 533-540, (1973)
[5] Orringer, Eustace, Wunsch, Et al., Natural history of lactic acidosis after grand-mal seizures, N Engl J Med, 297, pp. 796-799, (1977)
[6] Ralph, Rhabdomyolysis and acute renal failure, JACEP, 7, pp. 103-106, (1978)
[7] Herishanu, Landau, Diazepam in the treatment of strychnine poisoning, Br J Anaesth, 44, pp. 747-748, (1972)
[8] Jackson, Ng, Diggle, Et al., Strychnine poisoning treated successfully with diazepam, Br Med J, 3, pp. 519-520, (1971)

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