CARDIAC INVOLVEMENT IN HODGKIN DISEASE - REPORT OF A CASE STUDIED WITH ENDOMYOCARDIAL BIOPSY

A 24 year old female with a stage III-B Hodgkin disease involving the mediastinum was subjected to chemotherapy and supradiaphragmatic radiotherapy. A year later she developed heart failure. LV dilatation and decreased systolic function with anteroseptal and lateral hypokinesia and a small pericardial effusion were shown by X Ray and echo-cardiography. An initial clinical diagnosis of radiation heart disease was changed to myocardial involvement by Hodgkin disease after performing and endomyocardial biopsy.