Lung stereotactic body radiotherapy after past ablative therapy: a single institution case series

被引:1
作者
Wegner, Rodney E. [1 ]
Ahmed, Nissar [1 ]
Hasan, Shaakir [1 ]
Schumacher, Lana Y. [2 ]
Colonias, Athanasios [1 ]
机构
[1] Allegheny Hlth Network, Div Radiat Oncol, Canc Inst, 320 E North Ave, Pittsburgh, PA 15212 USA
[2] Allegheny Hlth Network, Esophagus & Lung Inst, 320 E North Ave, Pittsburgh, PA 15212 USA
关键词
brachytherapy; lung cancer; radiofrequency ablation; SBRT; vicryl mesh;
D O I
10.2217/lmt-2018-0012
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Aim: Non-small-cell lung cancer recurs locally 10-40% of the time after local therapy, presenting a therapeutic challenge given poor pulmonary reserve. Herein, we seek to evaluate the safety and efficacy of stereotactic body radiotherapy (SBRT) for retreatment of such patients. Methods: We identified and reviewed clinical outcomes in ten patients with recurrent non-small-cell lung cancer after past vicryl mesh brachytherapy. Results: Ten patients with a median age of 77 were treated to a median dose of 48 Gy in five fractions. Local control at 1 year was 88%. There was one distant failure at 29 months. There was no significant toxicity after SBRT. Conclusion: SBRT is safe and effective when used for re-irradiation after past ablative therapies.
引用
收藏
页数:8
相关论文
共 21 条
[1]   Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening [J].
Aberle, Denise R. ;
Adams, Amanda M. ;
Berg, Christine D. ;
Black, William C. ;
Clapp, Jonathan D. ;
Fagerstrom, Richard M. ;
Gareen, Ilana F. ;
Gatsonis, Constantine ;
Marcus, Pamela M. ;
Sicks, JoRean D. .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (05) :395-409
[2]   Outcome in a Prospective Phase II Trial of Medically Inoperable Stage I Non-Small-Cell Lung Cancer Patients Treated With Stereotactic Body Radiotherapy [J].
Baumann, Pia ;
Nyman, Jan ;
Hoyer, Morten ;
Wennberg, Berit ;
Gagliardi, Giovanna ;
Lax, Ingmar ;
Drugge, Ninni ;
Ekberg, Lars ;
Friesland, Signe ;
Johansson, Karl-Axel ;
Lund, Jo-Asmund ;
Morhed, Elisabeth ;
Nilsson, Kristina ;
Levin, Nina ;
Paludan, Merete ;
Sederholm, Christer ;
Traberg, Anders ;
Wittgren, Lena ;
Lewensohn, Rolf .
JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (20) :3290-3296
[3]   Early stage medically inoperable non-small cell lung cancer [J].
Jeffrey A. Bogart ;
Ernest Scalzetti ;
Elisabeth Dexter .
Current Treatment Options in Oncology, 2003, 4 (1) :81-88
[4]   Comparison of the RECIST 1.0 and RECIST 1.1 in Non-Small Cell Lung Cancer Treated with Cytotoxic Chemotherapy [J].
Choi, Hyun Chang ;
Kim, Jung Han ;
Kim, Hyeong Su ;
Jung, Soong Goo ;
Hwang, Sang Muk ;
Ju, Sung Bae ;
Yang, Ik .
JOURNAL OF CANCER, 2015, 6 (07) :652-657
[5]  
COX DR, 1972, J R STAT SOC B, V34, P187
[6]  
Ester EC, 2013, J RADIOSURGERY SBRT, V3, P325
[7]   Impact of Brachytherapy on Local Recurrence Rates After Sublobar Resection: Results From ACOSOG Z4032 (Alliance), a Phase III Randomized Trial for High-Risk Operable Non-Small-Cell Lung Cancer [J].
Fernando, Hiran C. ;
Landreneau, Rodney J. ;
Mandrekar, Sumithra J. ;
Nichols, Francis C. ;
Hillman, Shauna L. ;
Heron, Dwight E. ;
Meyers, Bryan F. ;
DiPetrillo, Thomas A. ;
Jones, David R. ;
Starnes, Sandra L. ;
Tan, Angelina D. ;
Daly, Benedict D. T. ;
Putnam, Joe B., Jr. .
JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (23) :2456-U246
[8]   Salvage stereotactic body radiotherapy for locally recurrent non-small cell lung cancer after sublobar resection and I125 vicryl mesh brachytherapy [J].
Gill, Beant S. ;
Clump, David A. ;
Burton, Steven A. ;
Christie, Neil A. ;
Schuchert, Matthew J. ;
Heron, Dwight E. .
FRONTIERS IN ONCOLOGY, 2015, 5
[9]  
Ginsberg RJ., 1995, ANN THORAC SURG, V60, P615, DOI [DOI 10.1016/0003-4975(95)00537-U, 10.1016/0003-4975]
[10]  
Ginsberg Robert J., 1995, Annals of Thoracic Surgery, V60, P615, DOI 10.1016/0003-4975(95)00537-U