CHRONIC GRANULOCYTIC-LEUKEMIA PRESENTING WITH AN EXTRAMEDULLARY T-LYMPHOBLASTIC CRISIS

被引：11

作者：

JACOB, A ^{[1
]}

ROWLANDS, DC ^{[1
]}

PATTON, N ^{[1
]}

HOLMES, JA ^{[1
]}

机构：

[1] QUEEN ELIZABETH HOSP,DEPT HISTOPATHOL,BIRMINGHAM B15 2TH,W MIDLANDS,ENGLAND

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 1994年 / 88卷 / 02期

关键词：

CHRONIC GRANULOCYTIC LEUKEMIA; EXTRAMEDULLARY T LYMPHOBLASTIC;

D O I：

10.1111/j.1365-2141.1994.tb05050.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 33-year-old man presented with hepatosplenomegaly and lymphadenopathy. Bone marrow findings were consistent with Philadelphia-positive accelerated-phase chronic granulocytic leukaemia (CGL). Lymph node histology and immunhistochemistry were diagnostic of T lymphoblastic lymphoma. Molecular studies on lymph node DNA identified rearrangement within the major breakpoint cluster region (M-bcr), indicating a common clonal origin of CGL and the T lymphoblastic lymphoma. We report the second case where extramedullary T lymphoblastic crisis was the presenting feature of CGL.

引用

页码：435 / 436

页数：2

共 12 条

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DERMATOLOGICA, 1991, 183 (01): : 47 - 48
[6] Acute lymphocytic blast crisis as an ocular manifestation of chronic granulocytic leukemia
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Popa, Gheorghe
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PEDIATRIC AND DEVELOPMENTAL PATHOLOGY, 2017, 20 (01) : 58 - 62

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