BIOSYNTHESIS OF PORPHYRINS AND RELATED MACROCYCLES .42. PULSE LABELING EXPERIMENTS CONCERNING THE TIMING OF COBALT INSERTION DURING VITAMIN-B-12 BIOSYNTHESIS

被引:29
作者
BALACHANDRAN, S
VISHWAKARMA, RA
MONAGHAN, SM
PRELLE, A
STAMFORD, NPJ
LEEPER, FJ
BATTERSBY, AR
机构
[1] University Chemical Laboratory, Cambridge CB2 1EW, Lensfield Road
来源
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1994年 / 05期
关键词
D O I
10.1039/p19940000487
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Pulse labelling experiments using Co-60(2+) and [methyl-C-13,C-14]-S-adenosyl-L-methionine have established that in the anaerobic organism Propionibacterium shermanii cobalt is inserted into the macrocycle after the second and before the fourth C-methylation step.
引用
收藏
页码:487 / 491
页数:5
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