IDENTIFICATION OF A RAS GENE IN THE SLIME-MOLD PHYSARUM-POLYCEPHALUM

被引：8

作者：

KOZLOWSKI, P ^{[1
]}

FRONK, J ^{[1
]}

TOCZKO, K ^{[1
]}

机构：

[1] WARSAW UNIV, INST BIOCHEM, ZWIRKI WIGURY 93, PL-02089 WARSAW, POLAND

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1993年 / 1173卷 / 03期

关键词：

GTP-BINDING PROTEIN; PALMITOYLATION; PRENYLATION; SEQUENCE HOMOLOGY; (P-POLYCEPHALUM);

D O I：

10.1016/0167-4781(93)90139-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A ras homologue was identified in the cDNA library from the slime mold Physarum polycephalum. The cDNA codes for a protein of 189 amino acids, showing high homology to ras genes from other organisms, especially to these from Dictyostelium discoideum. Amino acid sequence at the C-terminus of the putative protein suggests that unlike most other ras proteins, it is not palmitoylated and bears a geranylgeranyl rather than farnesyl chain.

引用

页码：357 / 359

页数：3

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