IMMUNOLOGICAL FUNCTIONS OF THE PULMONARY EPITHELIUM

被引：134

作者：

THOMPSON, AB ^{[1
]}

ROBBINS, RA ^{[1
]}

ROMBERGER, DJ ^{[1
]}

SISSON, JH ^{[1
]}

SPURZEM, JR ^{[1
]}

TESCHLER, H ^{[1
]}

RENNARD, SI ^{[1
]}

机构：

[1] UNIV ESSEN GESAMTHSCH, FAC MED, RUHRLANDKLIN, DIV PNEUMOL, ESSEN, GERMANY

来源：

EUROPEAN RESPIRATORY JOURNAL | 1995年 / 8卷 / 01期

关键词：

AIRWAY; CHEMOTAXIS; EPITHELIAL CELLS; IMMUNOLOGY; INFLAMMATION; MORPHOLOGY;

D O I：

10.1183/09031936.95.08010127

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The mature pulmonary epithelium forms a continuous lining to the airspace, Recent data suggest that this specialized epithelium may also contribute to host defence via interactions with inflammatory cells, Pulmonary epithelial cells can serve as part of the local immune system, providing structures and functions crucial for the maintenance of normal pulmonary function. This article will briefly review the morphology and development of the pulmonary epithelial cells, their function with regard to host defence, alterations of the pulmonary epithelium associated with airway diseases, and potential therapeutic implications for the treatment of respiratory diseases.

引用

页码：127 / 149

页数：23

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