ANTIEMETIC EFFICACY OF TROPISETRON IN PATIENTS FAILING PREVIOUS ANTIEMETIC THERAPY

被引：0
|
作者：
FALKSON, CI
FALKSON, HC
机构：
来源：
ONCOLOGY | 1995年 / 52卷 / 05期
关键词：
TROPISETRON; ANTIEMETIC EFFICACY; 5HT(3) ANTAGONIST;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Tropisetron was studied for efficacy and safety in 164 patients who were refractory to other antiemetic agents. 5 mg tropisetron was given intravenously, followed by 5 mg by mouth per day for 4 days. Complete prevention of nausea and vomiting was documented in 42% of patients on day 1 of cycle 1. Delayed nausea and vomiting were prevented in 41% in the first cycle. The antiemetic control did not decrease with subsequent cycles. Side effects ascribed to tropisetron were mild.
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页码：427 / 431
页数：5
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