EFFECTS OF BROMOCRIPTINE ON PERIODIC LIMB MOVEMENTS IN HUMAN NARCOLEPSY

被引：40

作者：

BOIVIN, DB ^{[1
]}

LORRAIN, D ^{[1
]}

MONTPLAISIR, J ^{[1
]}

机构：

[1] HOP SACRE COEUR, CTR ETUD SOMMEIL, 5400 BOUL GOUIN OUEST, MONTREAL H4J 1C5, QUEBEC, CANADA

来源：

NEUROLOGY | 1993年 / 43卷 / 10期

关键词：

D O I：

10.1212/WNL.43.10.2134

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We studied the effects of bromocriptine on periodic limb movements in sleep (PLMS) of narcoleptic patients. Bromocriptine significantly reduced the number and index of PLMS without improving the nocturnal sleep disruption in that disorder. These results support the hypothesis that dopaminergic mechanisms are involved in the physiopathology of PLMS, and suggest that PLMS do not play a major role in the nocturnal sleep disruption of narcoleptic patients.

引用

页码：2134 / 2136

页数：3

共 10 条

[1] DOPAMINE-RECEPTOR AUTORADIOGRAPHY OF HUMAN NARCOLEPTIC BRAIN [J].

ALDRICH, MS ;

HOLLINGSWORTH, Z ;

PENNEY, JB .

NEUROLOGY, 1992, 42 (02) :410-415

[2]

BAKER T, 1987, SLEEP RES, V16, P302

[3] COMPARATIVE POLYSOMNOGRAPHIC STUDY OF NARCOLEPSY AND IDIOPATHIC CENTRAL-NERVOUS-SYSTEM HYPERSOMNIA [J].

BAKER, TL ;

GUILLEMINAULT, C ;

NINOMURCIA, G ;

DEMENT, WC .

SLEEP, 1986, 9 (01) :232-242

[4] THE EFFECTS OF L-DOPA ON PERIODIC LEG MOVEMENTS AND SLEEP ORGANIZATION IN NARCOLEPSY [J].

BOIVIN, DB ;

MONTPLAISIR, J ;

POIRIER, G .

CLINICAL NEUROPHARMACOLOGY, 1989, 12 (04) :339-345

[5] TREATMENT OF RESTLESS LEGS SYNDROME AND PERIODIC MOVEMENTS DURING SLEEP WITH L-DOPA - A DOUBLE-BLIND, CONTROLLED-STUDY [J].

BRODEUR, C ;

MONTPLAISIR, J ;

GODBOUT, R ;

MARINIER, R .

NEUROLOGY, 1988, 38 (12) :1845-1848

[6]

Coleman RM., 1982, SLEEPING WAKING DISO, P265

[7]

LORRAIN D, 1990, SLEEP RES, V19, P247

[8]

Mitler MM, 1982, SLEEPING WAKING DISO, P145

[9]

Rechtschaffen Allan, 1968, MANUAL STANDARDIZED

[10] A DOUBLE-BLIND RANDOMIZED CROSSOVER TRIAL OF BROMOCRIPTINE AND PLACEBO IN RESTLESS LEGS SYNDROME [J].

WALTERS, AS ;

HENING, WA ;

KAVEY, N ;

CHOKROVERTY, S ;

GIDROFRANK, S .

ANNALS OF NEUROLOGY, 1988, 24 (03) :455-458

← 1 →