ALTOHYRTIN-A, A POTENT ANTITUMOR MACROLIDE FROM THE OKINAWAN MARINE SPONGE HYRTIOS-ALTUM

被引：153
作者：
KOBAYASHI, M
AOKI, S
SAKAI, H
KAWAZOE, K
KIHARA, N
SASAKI, T
KITAGAWA, I
机构：
[1] OSAKA UNIV,FAC PHARMACEUT SCI,YAMADA OKA 1-6,SUITA,OSAKA 565,JAPAN
[2] KANAZAWA UNIV,CANC RES INST,KANAZAWA,ISHIKAWA 920,JAPAN
来源：
TETRAHEDRON LETTERS | 1993年 / 34卷 / 17期
关键词：
D O I：
10.1016/S0040-4039(00)73564-7
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Altohyrtin A (1) has been isolated from the Okinawan marine sponge Hyrtios altum and the plane structure and parts of its relative configurations elucidated. Altohyrtin A (1) exhibited extremely potent cytotoxicity against KB cells at IC50 0.01 ng/ml.
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页码：2795 / 2798
页数：4
相关论文
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[1]  
FUSETANI N, COMMUNICATION
[2]  
KOBAYASHI M, 1992, CHEM PHARM BULL, V40, P1773
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