ELEVATED 1,25-DIHYDROXYVITAMIN-D PLASMA-LEVELS IN NORMAL HUMAN PREGNANCY AND LACTATION

被引：315

作者：

KUMAR, R ^{[1
]}

COHEN, WR ^{[1
]}

SILVA, P ^{[1
]}

EPSTEIN, FH ^{[1
]}

机构：

[1] HARVARD UNIV,BETH ISRAEL HOSP,SCH MED,THORNDIKE LAB,DEPT OBSTET & GYNECOL,BOSTON,MA 02215

来源：

JOURNAL OF CLINICAL INVESTIGATION | 1979年 / 63卷 / 02期

关键词：

D O I：

10.1172/JCI109308

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Plasma 1,25-dihydroxyvitamin D levels are elevated in early pregnancy and continue to increase throughout pregnancy. They remain elevated postpartum in lactating women. The elevated levels probably represent a physiological response to increased calcium requirements.

引用

页码：342 / 344

页数：3

共 18 条

[1] ELEVATED SERUM LEVELS OF 1-ALPHA, 25-DIHYDROXYCHOLECALCIFEROL IN LACTATING RATS [J].

BOASS, A ;

TOVERUD, SU ;

MCCAIN, TA ;

PIKE, JW ;

HAUSSLER, MR .

NATURE, 1977, 267 (5612) :630-632

[2] MICRODETERMINATION OF PHOSPHORUS [J].

CHEN, PS ;

TORIBARA, TY ;

WARNER, H .

ANALYTICAL CHEMISTRY, 1956, 28 (11) :1756-1758

[3] PHYSIOLOGIC HYPERPARATHYROIDISM IN PREGNANCY [J].

CUSHARD, WG ;

CREDITOR, MA ;

REISS, E ;

CANTERBURY, JM .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1972, 34 (05) :767-+

[4] METABOLISM AND MECHANISM OF ACTION OF VITAMIN-D1 [J].

DELUCA, HF ;

SCHNOES, HK .

ANNUAL REVIEW OF BIOCHEMISTRY, 1976, 45 :631-666

[5] SENSITIVE, PRECISE, AND CONVENIENT METHOD FOR DETERMINATION OF 1,25-DIHYDROXYVITAMIN-D IN HUMAN-PLASMA [J].

EISMAN, JA ;

HAMSTRA, AJ ;

KREAM, BE ;

DELUCA, HF .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1976, 176 (01) :235-243

[6] CONTROL OF 25-HYDROXYCHOLECALCIFEROL METABOLISM BY PARATHYROID GLANDS [J].

GARABEDIAN, M ;

BOYLE, IT ;

HOLICK, MF ;

DELUCA, HF .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1972, 69 (07) :1673-+

[7] COMPETITIVE PROTEIN-BINDING RADIOASSAY FOR 25-HYDROXYCHOLECALCIFEROL [J].

HADDAD, JG .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1971, 33 (06) :992-+

[8] CALCIUM METABOLISM IN NORMAL HUMAN PREGNANCY [J].

HEANEY, RP ;

SKILLMAN, TG .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1971, 33 (04) :661-+

[9] REGULATION OF SERUM 1-ALPHA,25-DIHYDROXYVITAMIN-D3 BY CALCIUM AND PHOSPHATE IN RAT [J].

HUGHES, MR ;

BRUMBAUGH, PF ;

HAUSSLER, MR ;

WERGEDAL, JE ;

BAYLINK, DJ .

SCIENCE, 1975, 190 (4214) :578-580

[10]

JOSINOVICH JB, 1969, FETAL HOMEOSTASIS, V4, P109

← 1 2 →