COEXISTENT GOUT AND RHEUMATOID-ARTHRITIS - CASE-REPORT AND LITERATURE-REVIEW

被引：61

作者：

WALLACE, DJ

KLINENBERG, JR

MORHAIM, D

BERLANSTEIN, B

BIREN, PC

CALLIS, G

机构：

[1] CEDARS SINAI MED CTR,DEPT MED,LOS ANGELES,CA 90048

[2] UNIV CALIF LOS ANGELES,SCH MED,LOS ANGELES,CA 90024

来源：

ARTHRITIS AND RHEUMATISM | 1979年 / 22卷 / 01期

关键词：

D O I：

10.1002/art.1780220113

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 73‐year‐old woman with Felty's syndrome and arthritis mutilans of long duration presented with tophaceous gout. The 7 previously reported cases of coexistent gout and rheumatoid arthritis (RA) are critically reviewed. Possible explanations for the rare coexistence of RA and gout are discussed: if uric acid is an inhibitor of the immune response, then hyperuricemia and gout could protect against development of RA. Conversely, crystalline protein binding may be a critical factor in the pathogenesis of gout, and the presence of abnormal proteins in RA could protect against gout. Copyright © 1979 American College of Rheumatology

引用

页码：81 / 86

页数：6

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