(R)-O-ARYLLACTIC ACIDS - CONVENIENT CHIRAL SOLVATING AGENTS FOR DIRECT H-1-NMR DETERMINATION OF THE ENANTIOMERIC COMPOSITION OF AMINES AND AMINO-ALCOHOLS

被引：20

作者：

CHINCHILLA, R ^{[1
]}

FOUBELO, F ^{[1
]}

NAJERA, C ^{[1
]}

YUS, M ^{[1
]}

机构：

[1] UNIV ALICANTE,FAC CIENCIAS,DEPT QUIM ORGAN,E-03080 ALACANT,SPAIN

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 08期

关键词：

D O I：

10.1016/0957-4166(95)00241-G

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

(R)-O-(4-Chloro-2-methylphenyl)- and (R)-O-(2-naphthyl)lactic acids are very efficent chiral solvating agents for the direct H-1 NMR assay of the enantiomeric composition especially for primary and secondary amines and significant amino alcohols such as propranalol and fluoxetine.

引用

页码：1877 / 1880

页数：4

共 15 条

[1]

BAXTER CAR, 1972, TETRAHEDRON LETT, P3357

[2] ENANTIOMERICALLY PURE GUANIDINE-CATALYZED ASYMMETRIC NITROALDOL REACTION [J].

CHINCHILLA, R ;

NAJERA, C ;

SANCHEZAGULLO, P .

TETRAHEDRON-ASYMMETRY, 1994, 5 (07) :1393-1402

[3] KINETIC RESOLUTION OF RACEMIC ALCOHOLS WITH CHIRAL CARBOXYLIC-ACIDS AND DICYCLOHEXYLCARBODIIMIDE [J].

CHINCHILLA, R ;

NAJERA, C ;

YUS, M ;

HEUMANN, A .

TETRAHEDRON-ASYMMETRY, 1990, 1 (12) :851-854

[4]

DYLLICKBRENZING.R, 1980, J AM CHEM SOC, V102, P1166

[5]

EJCHART A, 1971, B ACAD POL SCI-CHIM, V19, P725

[6]

EJCHART A, 1971, B ACAD POL SCI-CHIM, V19, P731

[7] THE CONFORMATION OF DERIVATIVES OF O-ARYLLACTIC ACID USED AS CHIRAL REAGENTS IN STRUCTURE DETERMINATION - NMR AND X-RAY STRUCTURE-ANALYSIS OF DIASTEREOISOMERIC MENTHOL ESTERS [J].

HEUMANN, A .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1993, (14) :1113-1115

[8] FLUORINATED LACTIC ACIDS - EASILY ACCESSIBLE REAGENTS FOR THE ANALYSIS OF CHIRAL COMPOUNDS BY F-19 NMR-SPECTROSCOPY - F-19 NMR SEPARATION OF THE 8 ISOMERS OF MENTHOL [J].

HEUMANN, A ;

FAURE, R .

JOURNAL OF ORGANIC CHEMISTRY, 1993, 58 (05) :1276-1279

[9] RESOLUTION AND ABSOLUTE-CONFIGURATION OF 1,2,3,5,6,10B-BETA-HEXAHYDRO-6-ALPHA-PHENYLPYRROLO[2,1-A]ISOQUINOLINE (MCN-4612-Z) - A PROBLEM OF DETERMINATION OF THE ENANTIOMERIC PURITY FOR A TERTIARY AMINE [J].

MARYANOFF, BE ;

MCCOMSEY, DF .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1985, 22 (03) :911-914

[10] KINETIC RESOLUTION OF RACEMIC CARBOXYLIC-ACIDS AND ALCOHOLS WITH HOMOCHIRAL ALCOHOLS AND CARBOXYLIC-ACIDS, RESPECTIVELY, AND THE MUKAIYAMA OR PALOMO REAGENTS [J].

MAZON, A ;

NAJERA, C ;

YUS, M ;

HEUMANN, A .

TETRAHEDRON-ASYMMETRY, 1992, 3 (11) :1455-1466

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