INHIBITION OF CELL-DIVISION INITIATION BY AN IMBALANCE IN THE RATIO OF FTSA TO FTSZ

被引：110

作者：

DEWAR, SJ

BEGG, KJ

DONACHIE, WD

机构：

来源：

JOURNAL OF BACTERIOLOGY | 1992年 / 174卷 / 19期

关键词：

D O I：

10.1128/JB.174.19.6314-6316.1992

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Elevated levels of FtsA protein block cell division at a very early stage, similar to that caused by inhibition of the action of FtsZ. In contrast, overexpression of FtsA and FtsZ together does not block division. A specific ratio of FtsA to FtsZ protein, therefore, is required for cell division.

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页码：6314 / 6316

页数：3

相关论文

共 12 条

[1] CELL-SHAPE AND DIVISION IN ESCHERICHIA-COLI - EXPERIMENTS WITH SHAPE AND DIVISION MUTANTS [J].

BEGG, KJ ;

DONACHIE, WD .

JOURNAL OF BACTERIOLOGY, 1985, 163 (02) :615-622

[2] FTSZ RING STRUCTURE ASSOCIATED WITH DIVISION IN ESCHERICHIA-COLI [J].

BI, E ;

LUTKENHAUS, J .

NATURE, 1991, 354 (6349) :161-164

[3] STUDIES WITH FTSA-LACZ PROTEIN FUSIONS REVEAL FTSA LOCATED INNER-OUTER MEMBRANE JUNCTIONS [J].

CHON, YH ;

GAYDA, R .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1988, 152 (03) :1023-1030

[4] TRANSCRIPTIONAL REGULATION OF CELL-DIVISION GENES IN ESCHERICHIA-COLI [J].

DEWAR, SJ ;

KAGANZUR, V ;

BEGG, KJ ;

DONACHIE, WD .

MOLECULAR MICROBIOLOGY, 1989, 3 (10) :1371-1377

[5]

DONACHIE WD, 1984, MICROBIAL DEV, P27

[6]

KHATTAR MM, UNPUB

[7] DIFFERENTIAL TRANSLATION OF CELL-DIVISION PROTEINS [J].

MUKHERJEE, A ;

DONACHIE, WD .

JOURNAL OF BACTERIOLOGY, 1990, 172 (10) :6106-6111

[8] DNA-SEQUENCE AND TRANSCRIPTIONAL ORGANIZATION OF ESSENTIAL CELL-DIVISION GENES FTSQ AND FTSA OF ESCHERICHIA-COLI - EVIDENCE FOR OVERLAPPING TRANSCRIPTIONAL UNITS [J].

ROBINSON, AC ;

KENAN, DJ ;

HATFULL, GF ;

SULLIVAN, NF ;

SPIEGELBERG, R ;

DONACHIE, WD .

JOURNAL OF BACTERIOLOGY, 1984, 160 (02) :546-555

[9] FURTHER EVIDENCE FOR OVERLAPPING TRANSCRIPTIONAL UNITS IN AN ESCHERICHIA-COLI CELL ENVELOPE-CELL DIVISION GENE-CLUSTER - DNA-SEQUENCE AND TRANSCRIPTIONAL ORGANIZATION OF THE DDL FTSQ REGION [J].

ROBINSON, AC ;

KENAN, DJ ;

SWEENEY, J ;

DONACHIE, WD .

JOURNAL OF BACTERIOLOGY, 1986, 167 (03) :809-817

[10] INTERACTION OF FTSA AND PBP3 PROTEINS IN THE ESCHERICHIA-COLI SEPTUM [J].

TORMO, A ;

AYALA, JA ;

DEPEDRO, MA ;

ALDEA, M ;

VICENTE, M .

JOURNAL OF BACTERIOLOGY, 1986, 166 (03) :985-992