Electrocatalytic multicomponent assembling of aldehydes, dimedone and 1-naphthylamine for synthesis of novel tetrahydrobenzo[c]acridin-8(7H)-one derivatives

被引：0
作者：
Heravi, Mohammad Reza Poor [1 ]
Karami, Hassan [1 ]
Mohammadi, Bagher [1 ]
Azizkhani, Vahid [1 ]
Ghelichkhani, Azadeh [1 ]
机构：
[1] Payame Noor Univ, Dept Chem, POB 19395-3697, Tehran, Iran
来源：
IRANIAN CHEMICAL COMMUNICATION | 2018年 / 6卷 / 04期
关键词：
Electrolysis transformation; electrogenerated base; multicomponent reaction; acridine; dimedone; 1-naphthyl amine;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient and convenient synthesis of novel tetrahydrobenzo[c]acridin-8(7H)-one derivatives is described using the electrogenerated anion of acetonitriles as the base in the presence of tetrabutylammonium fluoride as an effective supporting electrolyte in a one-pot, three-component condensation of aromatic aldehyde, dimedone and 1-naphthyl amine. The reaction carried out in an undivided cell containing an iron cathode and a graphite anode under a constant current density of 5 mA/cm(2) (I=20 mA, electrode surface=5 cm(2)) in CH3CN at room temperature was found to be optimum for the electrochemically induced chain process and resulted in the highest yield.
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页码：380 / 388
页数：9
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