DEPLETION OF O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE ACTIVITY IN MAMMALIAN-TISSUES AND HUMAN-TUMOR XENOGRAFTS IN NUDE-MICE BY TREATMENT WITH O-6-METHYLGUANINE

被引：43
作者：
DOLAN, ME
LARKIN, GL
ENGLISH, HF
PEGG, AE
机构：
[1] PENN STATE UNIV,MILTON S HERSHEY MED CTR,COLL MED,DIV ENDOCRINOL,HERSHEY,PA 17033
[2] PENN STATE UNIV,MILTON S HERSHEY MED CTR,COLL MED,DIV UROL,HERSHEY,PA 17033
[3] PENN STATE UNIV,MILTON S HERSHEY MED CTR,COLL MED,CANC RES CTR,HERSHEY,PA 17033
来源：
CANCER CHEMOTHERAPY AND PHARMACOLOGY | 1989年 / 25卷 / 02期
关键词：
D O I：
10.1007/BF00692348
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：103 / 108
页数：6
相关论文
共 43 条
[1]   INHIBITION OF O-6-ALKYLGUANINE-DNA-ALKYLTRANSFERASE ACTIVITY POTENTIATES CYTOTOXICITY AND INDUCTION OF SCES IN HUMAN GLIOMA-CELLS RESISTANT TO 1,3-BIS(2-CHLOROETHYL)-1-NITROSOUREA [J].
AIDA, T ;
CHEITLIN, RA ;
BODELL, WJ .
CARCINOGENESIS, 1987, 8 (09) :1219-1223
[2]  
ANDERSON T, 1976, CANCER TREAT REP, V60, P761
[3]   SYNTHESIS OF POTENTIAL ANTICANCER AGENTS .25. PREPARATION OF 6-ALKOXY-2-AMINOPURINES [J].
BALSIGER, RW ;
MONTGOMERY, JA .
JOURNAL OF ORGANIC CHEMISTRY, 1960, 25 (09) :1573-1575
[4]  
BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3
[5]  
BRENT TP, 1984, CANCER RES, V44, P1887
[6]   INCREASED CYTOTOXICITY OF 1-(2-CHLOROETHYL)-1-NITROSO-3(4-METHYL)-CYCLOHEXYLUREA BY PRETREATMENT WITH O-6-METHYLGUANINE IN RESISTANT BUT NOT IN SENSITIVE HUMAN-MELANOMA CELLS [J].
DEMPKE, W ;
NEHLS, P ;
WANDL, U ;
SOLL, D ;
SCHMIDT, CG ;
OSIEKA, R .
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 1987, 113 (04) :387-391
[7]  
DOLAN ME, 1985, CANCER RES, V45, P6413
[8]  
DOLAN ME, 1988, CANCER RES, V48, P3603
[9]  
DOLAN ME, 1988, CANCER RES, V48, P1184
[10]   EXPOSURE OF HELA-CELLS TO O-6ALKYLGUANINES INCREASES SENSITIVITY TO THE CYTO-TOXIC EFFECTS OF ALKYLATING-AGENTS [J].
DOLAN, ME ;
CORSICO, CD ;
PEGG, AE .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1985, 132 (01) :178-185
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