FORENSIC VALIDATION OF THE STR SYSTEMS SE 33 AND TC 11

被引：165

作者：

WIEGAND, P ^{[1
]}

BUDOWLE, B ^{[1
]}

RAND, S ^{[1
]}

BRINKMANN, B ^{[1
]}

机构：

[1] FBI ACAD,CTR FORENS SCI RES & TRAINING,QUANTICO,VA 22135

来源：

INTERNATIONAL JOURNAL OF LEGAL MEDICINE | 1993年 / 105卷 / 06期

关键词：

SHORT TANDEM REPEATS; SE; 33; TC; 11; FORENSIC VALIDATION; POPULATION STUDIES;

D O I：

10.1007/BF01222114

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

Population studies on Caucasians from northwest Germany were carried out using the short tandem repeat (STR) systems SE 33 (Locus: ACTBP2) and TC 11 (Locus: 11p15.5). After electrophoresis in PAG26 alleles could be identified for SE 33 in a sample size of 180 unrelated individuals and 6 alleles were found for TC 11 in 110 individuals. The combined mean exclusion chance for both systems was 0.96 and the discrimination index 0.999. No significant deviations from Hardy-Weinberg equilibrium could be demonstrated. In a small sample of families (SE 33 - n = 21; TC 11 - n = 30) no new mutations could be found. Positive and reproducible results for both STRs could be obtained from 50 pg template DNA.

引用

页码：315 / 320

页数：6

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