Managing Chronic Pain in the Elderly: An Overview of the Recent Therapeutic Advancements

被引:66
作者
Ali, Asad [1 ,2 ]
Arif, Abdul Wahab [3 ]
Bhan, Chandur [4 ]
Kumar, Deepak [5 ]
Malik, Muhammad Bilal [6 ]
Sayyed, Zohaib [7 ]
Akhtar, Khawaja Hassan [8 ]
Ahmad, Malik Qistas [9 ]
机构
[1] CMH Lahore Med Coll, Med, Lahore, Pakistan
[2] Inst Dent, Lahore, Pakistan
[3] Shaikh Zayed Hosp, Med, Lahore, Pakistan
[4] Chandka Med Coll Hosp, Internal Med, Larkana, Pakistan
[5] Jinnah Postgrad Med Ctr, Internal Med, Karachi, Pakistan
[6] Shifa Coll Med, Internal Med, Islamabad, Pakistan
[7] Shaikh Khalifa Bin Zayed Al Nahyan Med & Dent Col, Pediat, Bahawalpur, Pakistan
[8] King Edward Med Univ, Internal Med, Mayo Hosp, Lahore, Pakistan
[9] Univ Arizona, Hematol Oncol, Canc Ctr, Tucson, AZ 85721 USA
来源
CUREUS | 2018年 / 10卷 / 09期
关键词
chronic pain; opioids; non-steroidal anti-inflammatory drugs (nsaid); quality improvement; geriatrics; neuropathic pain; topical agents; chronic illnesses; targeted therapy; pain management;
D O I
10.7759/cureus.3293
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A majority of the elderly suffer from chronic pain that significantly alters their daily activities and imposes an enormous burden on health care. Multiple comorbidities and the risk of polypharmacy in the elderly make it a challenge to determine the appropriate drug, dosage, and maintenance of therapy. Opioids are the most commonly used agents for this purpose in the elderly. The aim of this article is to discuss both the current well-established therapies used for managing chronic pain in the elderly and also the emerging newer therapies.
引用
收藏
页数:10
相关论文
共 50 条
[21]   Managing metastatic bone pain: The role of bisphosphonates [J].
Gralow, Julie ;
Tripathy, Debu .
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 2007, 33 (04) :462-472
[22]  
Henrie-Barrus Patricia, 2016, Health Psychol Open, V3, p2055102916648995, DOI 10.1177/2055102916648995
[23]   Assessment and measurement of pain in older adults [J].
Herr, KA ;
Garand, L .
CLINICS IN GERIATRIC MEDICINE, 2001, 17 (03) :457-+
[24]   International Union of Pharmacology. XXVII. Classification of cannabinoid receptors [J].
Howlett, AC ;
Barth, F ;
Bonner, TI ;
Cabral, G ;
Casellas, P ;
Devane, WA ;
Felder, CC ;
Herkenham, M ;
Mackie, K ;
Martin, BR ;
Mechoulam, R ;
Pertwee, RG .
PHARMACOLOGICAL REVIEWS, 2002, 54 (02) :161-202
[25]  
LANZA F, 1989, J RHEUMATOL, V16, P1570
[26]   A Comparative Investigation of Observational Pain Assessment Tools for Older Adults With Dementia [J].
Lints-Martindale, Amanda C. ;
Hadjistavropoulos, Thomas ;
Lix, Lisa M. ;
Thorpe, Lilian .
CLINICAL JOURNAL OF PAIN, 2012, 28 (03) :226-237
[27]   Pain relief from nasal salmon calcitonin in osteoporotic vertebral crush fractures - A double blind, placebo-controlled clinical study [J].
Lyritis, GP ;
Paspati, I ;
Karachalios, T ;
Ioakimidis, D ;
Skarantavos, G ;
Lyritis, PG .
ACTA ORTHOPAEDICA SCANDINAVICA, 1997, 68 :112-114
[28]   Mind-body interventions for chronic pain in older adults: A structured review [J].
Morone, Natalia E. ;
Greco, Carol M. .
PAIN MEDICINE, 2007, 8 (04) :359-375
[29]   The McGill Pain Questionnaire as a Multidimensional Measure in People with Cancer: An Integrative Review [J].
Ngamkham, Srisuda ;
Vincent, Catherine ;
Finnegan, Lorna ;
Holden, Janean F. ;
Wang, Zaijie Jim ;
Wilkie, Diana J. .
PAIN MANAGEMENT NURSING, 2012, 13 (01) :27-51
[30]   Brain Neuronal CB2 Cannabinoid Receptors in Drug Abuse and Depression: From Mice to Human Subjects [J].
Onaivi, Emmanuel S. ;
Ishiguro, Hiroki ;
Gong, Jian-Ping ;
Patel, Sejal ;
Meozzi, Paul A. ;
Myers, Lester ;
Perchuk, Alex ;
Mora, Zoila ;
Tagliaferro, Patricia A. ;
Gardner, Eileen ;
Brusco, Alicia ;
Akinshola, B. Emmanuel ;
Hope, Bruce ;
Lujilde, Javier ;
Inada, Toshiya ;
Iwasaki, Shinya ;
Macharia, David ;
Teasenfitz, Lindsey ;
Arinami, Tadao ;
Uhl, George R. .
PLOS ONE, 2008, 3 (02)