BONE-LESIONS IN HISTIOCYTOSIS-X

被引：52
作者：
BOLLINI, G
JOUVE, JL
GENTET, JC
JACQUEMIER, M
BOUYALA, JM
机构：
[1] Departments of Paediatric Orthopaedics, Hôpitul des Enfant s de la Timone, Marseille
[2] Departments of Paediatric Oncology, Hôpitul des Enfant s de la Timone, Marseille
来源：
JOURNAL OF PEDIATRIC ORTHOPAEDICS | 1991年 / 11卷 / 04期
关键词：
EOSINOPHILIC GRANULOMA; HISTIOCYTOSIS-X;
D O I：
10.1097/01241398-199107000-00009
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
Sixty-two patients with histiocytosis X were followed for an average of 5 years. The patients were classified into the groups: general visceral types (14 cases), multiple eosinophilic granulomas (nine cases), and solitary eosinophilic granulomas (39 cases). One hundred bony lesions were noted in 60 of the 62 patients. The bone lesions showed progressive improvement in single and multiple eosinophilic granulomas independent of treatment type. After biopsy, patients received no treatment unless there was a dangerous extension into the soft tissues because of its site, i.e., in the skull. In the general visceral types, chemotherapy was effective in visceral sites and in extensions of the tumor outside the bone but did not alter the natural history of the bony lesion.
引用
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页码：469 / 477
页数：9
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