PURIFICATION TO HOMOGENEITY OF CAMEL PITUITARY PRO-OPIOCORTIN, THE COMMON PRECURSOR OF OPIOID PEPTIDES AND CORTICOTROPIN

被引：57
作者：
KIMURA, S
LEWIS, RV
GERBER, LD
BRINK, L
RUBINSTEIN, M
STEIN, S
UDENFRIEND, S
机构：
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1979年 / 76卷 / 04期
关键词：
D O I：
10.1073/pnas.76.4.1756
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Pro-opiocortin was purified from camel pituitaries by procedures including high-performance liquid chromatography. The precursor relationship of the pure protein to the opioid peptides and to corticotropin was confirmed. Partial chemical analysis consisting of amino acid analysis and tryptic peptide mapping was carried out with the aid of sensitive fluorescence detection.
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页码：1756 / 1759
页数：4
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