Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health claims in relation to linoleic acid and "molecule precursors regulating cell functions (prostaglandins, leucotrienes)", maintenance of normal blood LDL-cholesterol concentrations and protection of the skin from UV-induced damage. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from stakeholders. The food constituent that is the subject of the health claims is linoleic acid. The Panel considers that linoleic acid is sufficiently characterised. "Molecule precursors regulating cell functions (prostaglandins, leucotrienes)" The claimed effect is "molecule precursors regulating cell functions (prostaglandins, leucotrienes)". The target population is assumed to be the general population. The claimed effect is not sufficiently defined, and the wordings, references and clarifications provided by Member States do not give any further information which could be used to define the claimed effect. The Panel considers that the claimed effect is general and non specific, and does not refer to any specific health claim as required by Regulation (EC) No 1924/2006. Maintenance of normal blood LDL-cholesterol concentrations The claimed effect is "artery/heart health". The target population is assumed to be the general population. From the clarifications provided by Member States, the Panel assumes that the claimed effect refers to maintenance of normal blood LDL-cholesterol concentrations. A claim on linoleic acid and maintenance of normal blood LDL-cholesterol concentrations has already been assessed with a favourable outcome. Protection of the skin from UV-induced damage The claimed effect is "correlation analyses on pooled data suggested that there may be less actinic skin damage with a higher intake of olive oil, a high intake of olive oil appeared to be protective against cutaneous actinic damage". The target population is assumed to be the general population. From the reference provided, the Panel assumes that the claimed effect refers to protection of the skin from UV-induced damage. The Panel considers that protection of the skin from UV-induced damage is a beneficial physiological effect. No references were provided from which conclusions could be drawn for the scientific substantiation of the claim. On the basis of the data presented, the Panel concludes that a cause and effect relationship has not been established between the dietary intake of linoleic acid and protection of the skin from UV-induced damage.