LAMOTRIGINE AS AN ADD-ON DRUG IN THE MANAGEMENT OF LENNOX-GASTAUT SYNDROME

被引：107
作者：
TIMMINGS, PL
RICHENS, A
机构：
[1] Department of Pharmacology and Therapeutics, University of Wales, College of Medicine, Cardiff
来源：
EUROPEAN NEUROLOGY | 1992年 / 32卷 / 06期
关键词：
LAMOTRIGINE; LENNOX-GASTAUT SYNDROME; ANTIEPILEPTIC DRUGS;
D O I：
10.1159/000116849
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We report our experience with lamotrigine add-on therapy in the treatment of 11 patients with Lennox-Gastaut syndrome. Lamotrigine is a novel antiepileptic drug, chemically unrelated to the major anticonvulsants in current use. Ten patients experienced a > 50% reduction in seizure frequency, 1 patient experienced no change in seizure frequency. All patients tolerated lamotrigine satisfactorily and no side-effects were reported.
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页码：305 / 307
页数：3
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