Immunological parameters as a new lead in the diagnosis of ovarian cancer

被引：0
作者：
Baert, T. [1 ,2 ]
Timmerman, D. [1 ,3 ]
Vergote, I. [1 ,2 ]
Coosemans, A. [1 ,2 ]
机构：
[1] UZ Leuven, Gynaecol & Obstet, B-3000 Leuven, Belgium
[2] Katholieke Univ Leuven, Dept Oncol, Leuven Canc Inst, B-3000 Leuven, Belgium
[3] Katholieke Univ Leuven, Dept Dev & Regenerat, B-3000 Leuven, Belgium
来源：
FACTS VIEWS AND VISION IN OBGYN | 2015年 / 7卷 / 01期
基金：
比利时弗兰德研究基金会;
关键词：
Ovarian cancer; diagnosis; prognostic marker; immunosuppression; regulatory T cell; myeloid derived suppressor cells; tumor-associated macrophages;
D O I：
暂无
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Ovarian cancer is the leading cause of pelvic gynecological cancer death in Europe. Prognosis is poor in women diagnosed at stage III to IV or in case disease recurs. Platin-based chemotherapy and radical surgery have already improved prognosis significantly. Novel strategies in the treatment of ovarian cancer are being searched for. The study of the immune system as a valuable parameter in the development of ovarian cancer has been neglected for a long time. Nevertheless, this is a field in full progression and might open new perspectives in the diagnosis and prognosis of ovarian cancer patients and could lead to a more motivated choice of targeted therapies.
引用
收藏
页码：67 / 72
页数：6
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