DICING WITH DEATH - DISSECTING THE COMPONENTS OF THE APOPTOSIS MACHINERY

被引：402

作者：

MARTIN, SJ ^{[1
]}

GREEN, DR ^{[1
]}

COTTER, TG ^{[1
]}

机构：

[1] ST PATRICKS COLL,DEPT BIOL,CELL BIOL LAB,MAYNOOTH,KILDARE,IRELAND

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1994年 / 19卷 / 01期

关键词：

D O I：

10.1016/0968-0004(94)90170-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Apoptosis, a mode of cell death commonly observed when death is a desirable or programmed event, has several characteristic structural features. These features appear to be induced by a range of gene products which, together, supervise and participate in the controlled dismantling of the cell. In this article the molecular components of the apoptotic machinery and the proteins implicated in the regulation of this mechanism of cell death are discussed.

引用

页码：26 / 30

页数：5

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